Of, relating to, or designating a genetic mutation that alters a codon to code for a different amino acid, resulting in an amino acid substitution in the protein product of the gene.
Origin
1960s. From mis- + sense, after nonsense.
Definition of missense in US English:
missense
adjectiveˈmɪsˌs(ə)ns
Genetics
Of, relating to, or designating a genetic mutation that alters a codon to code for a different amino acid, resulting in an amino acid substitution in the protein product of the gene.