Late 19th century; earliest use found in T. Clifford Allbutt (1836–1925), physician. From macro- + ancient Greek μέλος limb + -ia, probably after French macromélie; compare earlier micromelia.
Definition of macromelia in US English:
macromelia
nounˌmakrə(ʊ)ˈmiːlɪə
Medicine
Abnormal enlargement of a limb.
Origin
Late 19th century; earliest use found in T. Clifford Allbutt (1836–1925), physician. From macro- + ancient Greek μέλος limb + -ia, probably after French macromélie; compare earlier micromelia.